Viruses
Past MDCAT Questions
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MCQ 1.1.1
What does the term bacteriophage refer to? (MDCAT 2022) |
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| A | a virus that infects bacteria | B | a bacterium that infects a virus | ||||
| C | a virus which behaves as a bacterium | D | a combination of a bacterium and a virion | ||||
| Solution:(a) The name means bacteria-eater, and that is what these viruses do. | |||||||
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MCQ 1.1.2
Which of the following viruses contains single stranded DNA? (MDCAT 2022) |
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| A | adenovirus | B | herpes virus | ||||
| C | parvovirus | D | poxvirus | ||||
| Solution:(c) The parvoviruses carry a single strand of DNA. | |||||||
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MCQ 1.1.3
How many tail fibrils are attached to the end plate of a bacteriophage? (MDCAT 2022) |
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| A | 2 | B | 4 | ||||
| C | 6 | D | 8 | ||||
| Solution:(c) Six fibrils spread from the end plate and hold the phage to the bacterial wall. | |||||||
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MCQ 1.1.4
Which of the following viruses contains single stranded DNA? (MDCAT 2023) |
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| A | adenovirus | B | herpes virus | ||||
| C | parvovirus | D | poxvirus | ||||
| Solution:(c) The parvoviruses are the single stranded DNA viruses; the other three carry double stranded DNA. | |||||||
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MCQ 1.1.5
An example of a virus having a polyhedral capsid with 252 capsomeres is: (MDCAT 2024) |
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| A | adenovirus | B | tobacco mosaic virus | ||||
| C | influenza virus | D | bacteriophage | ||||
| Solution:(a) The adenovirus capsid is an icosahedron built of 252 capsomeres. | |||||||
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MCQ 1.1.6
The causative organism of measles is: (MDCAT 2024) |
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| A | poxvirus | B | papovavirus | ||||
| C | picornavirus | D | paramyxovirus | ||||
| Solution:(d) Measles is caused by the measles virus, a paramyxovirus. | |||||||
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MCQ 1.1.7
In the life cycle of a bacteriophage, lysozyme is required in which step of the infection process? (MDCAT 2024) |
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| A | release of the new phages | B | penetration | ||||
| C | replication | D | adsorption | ||||
| Solution:(b) The enzyme digests a hole in the bacterial wall so the phage DNA can be injected. | |||||||
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MCQ 1.1.8
Why are retroviruses placed in a separate class of RNA viruses? (UHS MDCAT 2025) |
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| A | They always infect animal cells only | B | Their RNA acts directly as mRNA | ||||
| C | They lack protein coats | D | They use reverse transcriptase to make DNA from RNA | ||||
| Solution:(d) A retrovirus carries reverse transcriptase, which copies its RNA into DNA for the host to integrate. | |||||||
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MCQ 1.1.9
Which disease is caused by enveloped virus? (KMU MDCAT 2025) |
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| A | Leaf curl disease of cotton | B | Flu | ||||
| C | Polio | D | Hepatitis A | ||||
| Solution:(b) The influenza virus takes a lipid envelope from the host membrane as it leaves. | |||||||
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MCQ 1.1.10
On the basis of morphological classification, influenza virus is an example of: (KMU MDCAT 2025) |
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| A | Helical capsid virus | B | Polyhedral capsid virus | ||||
| C | Enveloped capsid virus | D | Non-enveloped capsid virus | ||||
| Solution:(c) Influenza is a helical virus wrapped in an envelope, so it is classed with the enveloped viruses. | |||||||
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MCQ 1.1.11
Which of the following virus is having double stranded RNA in its core? (NUMS MDCAT 2025) |
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| A | Small pox | B | Mild rash virus | ||||
| C | Diarrhea virus | D | Rubella virus | ||||
| Solution:(c) The rotavirus of infantile diarrhoea carries double stranded RNA. | |||||||
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MCQ 1.1.12
Pore size of porcelain filter ranges between: (NUMS MDCAT 2025) |
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| A | 10 – 100 nm | B | 100 – 1000 nm | ||||
| C | 10 – 10 μm | D | 100 – 1000 μm | ||||
| Solution:(b) A porcelain filter has pores of about 100 to 1000 nanometres, small enough to hold bacteria and let viruses through. | |||||||
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MCQ 1.1.13
Reverse transcriptase converts: (NUMS MDCAT 2025) |
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| A | ds RNA to ss RNA | B | ss RNA to ds RNA | ||||
| C | ss RNA to ds DNA | D | ss DNA to ds DNA | ||||
| Solution:(c) Reverse transcriptase copies the single stranded RNA of a retrovirus into double stranded DNA. | |||||||
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MCQ 1.1.14
Which group of viruses can cause diseases like influenza, measles and rabies? (SIBA MDCAT 2025) |
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| A | Plant viruses | B | Animal viruses | ||||
| C | Fungal viruses | D | Bacteriophages | ||||
| Solution:(b) Influenza, measles and rabies viruses all multiply in animal cells. | |||||||
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MCQ 1.1.15
Envelope in a virus is derived from (SZABMU MDCAT 2025) |
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| A | Host cell ribosomes | B | Host cell membrane | ||||
| C | Viral capsid proteins | D | Viral genome replication | ||||
| Solution:(b) An enveloped virus wraps itself in a piece of the host membrane as it buds out. | |||||||
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MCQ 1.1.16
The shape of Adenovirus is: (SZABMU MDCAT 2025) |
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| A | Helical shape | B | Tadpole shape | ||||
| C | Polyhedron shape | D | Circular shape | ||||
| Solution:(c) The adenovirus capsid is an icosahedron, that is a polyhedron. | |||||||
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MCQ 1.1.17
Example of viruses having a polyhedral capsid that is with 252 capsomeres is: (UHS MDCAT 2024) |
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| A | Adenovirus | B | Tobacco Mosaic Virus | ||||
| C | Influenza virus | D | Bacteriophage | ||||
| Solution:(a) The adenovirus capsid is an icosahedron built of 252 capsomeres. | |||||||
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MCQ 1.1.18
In the life cycle of a bacteriophage, the lysozymes are required in which of the following steps of infection process? (UHS MDCAT 2024) |
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| A | Genome injection | B | Penetration | ||||
| C | Replication | D | Adsorption | ||||
| Solution:(b) The tail lysozyme digests a hole in the bacterial wall so the genome can be driven in. | |||||||
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MCQ 1.1.19
The genetic code of ________ is bound by a lipid membrane? (KMU MDCAT 2024) |
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| A | Enterovirus | B | Flu virus | ||||
| C | Hepatitis A virus | D | Polio virus | ||||
| Solution:(b) The influenza virus takes a lipid envelope from the host membrane; the picornaviruses are naked. | |||||||
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MCQ 1.1.20
Viruses Can NOT _______. (KMU MDCAT 2024) |
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| A | Crystalize | B | Excrete | ||||
| C | Infect bacteria | D | Mutate | ||||
| Solution:(b) A virus has no metabolism of its own, so it neither feeds nor excretes. | |||||||
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MCQ 1.1.21
Which of the following is NOT true about viruses? (KMU MDCAT 2024) |
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| A | Contain DNA | B | Can replicate on their own | ||||
| C | Can infect bacteria | D | They have a sub-cellular structure | ||||
| Solution:(b) A virus can only be copied inside a host cell, using the machinery of that cell. | |||||||
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MCQ 1.1.22
Which of the following virus has a double stranded DNA genome? (NUMS MDCAT 2024) |
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| A | Rubella | B | Influenza | ||||
| C | HIV | D | Small pox | ||||
| Solution:(d) The smallpox virus carries double stranded DNA; the other three are RNA viruses. | |||||||
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MCQ 1.1.23
What of the following virus contains single stranded DNA? (UHS MDCAT 2023) |
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| A | Adeno virus | B | Herpes virus | ||||
| C | Parvo virus | D | Pox virus | ||||
| Solution:(c) The parvoviruses are the smallest DNA viruses and their genome is a single strand. | |||||||
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MCQ 1.1.24
How may tail fibrils are attached to the end plate of a bacteriophage? (UHS MDCAT 2023) |
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| A | 2 | B | 4 | ||||
| C | 6 | D | 8 | ||||
| Solution:(c) Six tail fibres spread from the end plate and hold the phage to the bacterial wall. | |||||||
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MCQ 1.1.25
All viruses are: (SZABMU MDCAT 2023) |
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| A | Autotrophs | B | Heterotrophs | ||||
| C | Parasites | D | Predators | ||||
| Solution:(c) A virus can multiply only inside a living cell, so every virus is an obligate parasite. | |||||||
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MCQ 1.1.26
The complete, mature and infectious virus particle is known as: (NUMS MDCAT 2023) |
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| A | Venome | B | Genome | ||||
| C | Virion | D | Capsid | ||||
| Solution:(c) A complete infectious virus particle is a virion. | |||||||
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MCQ 1.1.27
Virus is what type of agent? (UHS MDCAT 2023) |
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| A | Cellular agent | B | Infectious agent | ||||
| C | Non-infectious agent | D | Non-protein agent | ||||
| Solution:(b) A virus can do nothing but infect a living cell and multiply in it. | |||||||
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MCQ 1.1.28
Viruses usually are limited to specific hosts because: (PMC MDCAT 2022) |
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| A | They contain either DNA or RNA | B | They contain protein | ||||
| C | They are specific to cell receptors | D | They are capable to divide with in the host body | ||||
| Solution:(c) A virus can enter only a cell whose surface carries the receptor its coat proteins fit. | |||||||
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MCQ 1.1.29
A virologist who studies viruses in great detail which of the following would he use? (PMC MDCAT 2022) |
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| A | Compound microscope | B | Porcelain filters | ||||
| C | Electron microscope | D | CT scan machine | ||||
| Solution:(c) A virus is far below the resolving power of a light microscope. | |||||||
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MCQ 1.1.30
Which of the following was the first virus to be isolated and studied under the electron microscope: (PMC MDCAT 2022) |
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| A | HIV | B | Rabies Virus | ||||
| C | Pox Viruses | D | TMV | ||||
| Solution:(d) Tobacco mosaic virus was the first virus isolated and the first seen under the electron microscope. | |||||||
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MCQ 1.1.31
Which of the following is incorrect about virus? (PMC MDCAT 2022) |
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| A | Viruses are intracellular parasites | B | Viruses cannot attack upon prokaryotes | ||||
| C | Viruses contain genetic information and have a capsid protein coat | D | Viruses cannot survive without a host | ||||
| Solution:(b) Bacteriophages attack bacteria, which are prokaryotes. | |||||||
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MCQ 1.1.32
The viruses who can attack the bacteria are known as: (PMC MDCAT 2022) |
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| A | Retrovirus | B | Pox virus | ||||
| C | Bacteriophage | D | Oncovirus | ||||
| Solution:(c) A virus that infects a bacterium is a bacteriophage. | |||||||
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MCQ 1.1.33
Which of the following virus has complex capsid that consists of polyhedral head and helical tall? (PMC MDCAT 2022) |
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| A | Influenza virus | B | Herpes virus | ||||
| C | Bacteriophage | D | Human Immuno Deficiency virus | ||||
| Solution:(c) A T-even bacteriophage has a polyhedral head and a helical tail. | |||||||
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MCQ 1.1.34
Poxviruses are: (PMC MDCAT 2022) |
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| A | Double stranded DNA virus | B | Single stranded RNA virus | ||||
| C | Single stranded DNA virus | D | Protein virus | ||||
| Solution:(a) The poxviruses carry a large double stranded DNA genome. | |||||||
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MCQ 1.1.35
A virus has its genome which is enclosed by a protein coat, called: (PMC MDCAT 2022) |
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| A | Spore | B | Capsid | ||||
| C | Envelope | D | Shell | ||||
| Solution:(b) The protein coat round the viral genome is the capsid. | |||||||
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MCQ 1.1.36
Viruses are able to recognize the host surface by means of their: (PMC MDCAT 2022) |
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| A | Capsid | B | Spikes | ||||
| C | DNA | D | RNA | ||||
| Solution:(b) The spikes of the envelope fit the receptors of the host cell. | |||||||
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MCQ 1.1.37
Which one can be considered as living characteristic of a virus: (NUMS MDCAT 2022) |
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| A | Can be crystallized | B | No cellular respiration | ||||
| C | Mutate their genetic | D | Lack biosynthetic machinery | ||||
| Solution:(c) Mutation of its genetic material is the one thing a virus does that living things do. | |||||||
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MCQ 1.1.38
What is the function of the lysozyme enzyme released by bacteriophages? (PMC Practice 2021) |
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| A | Injecting DNA | B | Replication | ||||
| C | Dissolve bacterial cell wall | D | All of these | ||||
| Solution:(c) The tail lysozyme digests a hole in the bacterial wall so the genome can be driven in. | |||||||
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MCQ 1.1.39
What is the viral envelope composed of? (PMC Practice 2021) |
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| A | Proteins | B | Glycoproteins | ||||
| C | Lipids and proteins | D | All of the above | ||||
| Solution:(d) The envelope is a piece of the host membrane, lipid and protein, with viral glycoprotein spikes in it. | |||||||
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MCQ 1.1.40
Icosahedral Viruses have how many faces? (PMC Practice 2021) |
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| A | 20 | B | 30 | ||||
| C | 10 | D | 40 | ||||
| Solution:(a) An icosahedron has twenty triangular faces. | |||||||
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MCQ 1.1.41
_________ refers to the breakdown or removal of the capsid. (PMC Practice 2021) |
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| A | Assembly | B | Uncoating | ||||
| C | Integration | D | Maturation | ||||
| Solution:(b) Uncoating is the stripping of the capsid that frees the viral genome inside the host cell. | |||||||
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MCQ 1.1.42
Which of the following is not related to the enveloped virus? (PMC MDCAT 2020) |
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| A | They survive for a long time | B | Their envelope is not sensitive to sunlight | ||||
| C | They are tolerant to antibodies | D | Envelope is derived from host | ||||
| Solution:(b) The lipid envelope is easily damaged by sunlight, drying and detergents. | |||||||
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MCQ 1.1.43
The complete, mature and infection virus particle is known as: (PMC MDCAT 2020) |
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| A | Venome | B | Genome | ||||
| C | Virion | D | Capsid | ||||
| Solution:(c) A complete infectious virus particle is a virion. | |||||||
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MCQ 1.1.44
The protein coat of virus is called: (UHS MDCAT 2019) |
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| A | Capsid | B | Cosmid | ||||
| C | Capsomere | D | Chromophore | ||||
| Solution:(a) The protein coat of a virus is its capsid. | |||||||
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MCQ 1.1.45
In viruses, a combined structure formed by core (Nucleic Acid) and capsid is: (UHS MDCAT 2018) |
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| A | Nucleocapsid | B | Prion | ||||
| C | Envelope | D | Capsomeres | ||||
| Solution:(a) The genome with its capsid together are the nucleocapsid. | |||||||
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MCQ 1.1.46
Phages which show lysogenic cycle are known as: (UHS MDCAT 2018) |
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| A | Enveloped Phage | B | Virulent Phage | ||||
| C | Temperate phages | D | Bacteriophage | ||||
| Solution:(c) A temperate phage integrates its genome and lies dormant instead of bursting the cell at once. | |||||||
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MCQ 1.1.47
Size of virus ranges in: (UHS MDCAT 2017) |
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| A | 20 to 250 nm | B | 25 to 250 nm | ||||
| C | 25 to 300 nm | D | 20 to 300 nm | ||||
| Solution:(a) Viruses run from about $20$ to $250\,\mathrm{nm}$ across. | |||||||
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MCQ 1.1.48
All viruses can reproduce within living organisms only, so they are known as: (UHS MDCAT 2016) |
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| A | Ectoparasites | B | Endoparasites | ||||
| C | Obligative Intracellular Parasites | D | Facultative Intracellular Parasites | ||||
| Solution:(c) A virus can multiply only inside a living cell, so it is an obligate intracellular parasite. | |||||||